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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant Human APRIL/TNFSF13/CD256/TALL248T￥ 16001
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Recombinant Human APRIL/TNFSF13/CD256/TALL296T￥ 26001
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Recombinant Human APRIL/TNFSF13/CD256/TALL2GV-P01466-10ug￥ 1176.001
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Recombinant Human APRIL/TNFSF13/CD256/TALL2GV-P01466-50ug￥ 3000.001
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Recombinant Human APRIL/TNFSF13/CD256/TALL2GV-P01466-500ug￥ 16000.001
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Recombinant Human APRIL/TNFSF13/CD256/TALL2GV-P01466-1mg￥ 22200.001
产品简介
| Known as | Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256; TNFSF13 |
| Derived from | Human Cells |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Reconstitution | Dissolve the lyophilized protein in distilled water. |
| Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
| Background | APRIL (a proliferation-inducingligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely ofa single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signalthrough the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL binds to heparan sulfateproteoglycans (HSPGs) independently of its binding to TACI and BCMA. APRIL can form bioactive heterotrimers withBAFF, and these circulate in the serum of patients with rheumatic immune disorders. APRIL enhances the proliferation and survival of plasma cells andalso promotes T cell-dependenthumoral responses. APRIL levels are elevated inthe serum during coronary artery disease, and it is also elevated in many cancers primarily due to expression by tumor-infiltratingneutrophils. |
| 规格 | 10ug50ug500ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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