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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant Human Scavenger Receptor Class B Membe48T/96T￥ 23001
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Recombinant Human Scavenger Receptor Class B MembeGV-P01677-10ug￥ 1536.001
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Recombinant Human Scavenger Receptor Class B MembeGV-P01677-50ug￥ 4280.001
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Recombinant Human Scavenger Receptor Class B MembeGV-P01677-500ug￥ 13520.001
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Recombinant Human Scavenger Receptor Class B MembeGV-P01677-1mg￥ 18800.001
产品简介
| Known as | Lysosome Membrane Protein 2; 85 kDa Lysosomal Membrane Sialoglycoprotein; LGP85; CD36 Antigen-Like 2; Lysosome Membrane Protein II; LIMP II; Scavenger Receptor Class B Member 2; CD36; SCARB2; CD36L2; LIMPII |
| Derived from | Human Cells |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.Immobilized Human IL-20 (Cat#C147) at 2μg/ml (100 μl/well) can bind Human IL-20RA-His(Cat#C614).The ED50 of Human IL-20RA-His(Cat#C614)is 3.5 ug/ml . |
| Background | Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, SCARB2 also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. |
| 规格 | 10ug50ug500ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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