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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant Human Caspase-10/CASP1048T/96T￥ 0.001
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Recombinant Human Caspase-10/CASP10GV-P01759-10ug￥ 1800.001
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Recombinant Human Caspase-10/CASP10GV-P01759-50ug￥ 4720.001
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Recombinant Human Caspase-10/CASP10GV-P01759-500ug￥ 14640.001
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Recombinant Human Caspase-10/CASP10GV-P01759-1mg￥ 20400.001
产品简介
| Known as | Caspase-10; CASP-10; Apoptotic Protease Mch-4; FAS-Associated Death Domain Protein Interleukin-1B-Converting Enzyme 2; FLICE2; ICE-Like Apoptotic Protease 4; CASP10; MCH4 |
| Derived from | E.coli |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation | Supplied as a 0.2 μm filtered solution of 25mM HEPES, 10mM DTT, pH 7.5. |
| Storage | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
| Background | Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7). CASP10 cleaves and activates caspases 3 and 7, but itself is processed by caspase 8. Defects in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. |
| 规格 | 10ug50ug500ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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