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热门关键词：白介素 gibco ELISA试剂盒胎牛血清移液器 ※本公司产品仅供科研实验研究使用，不用于临床诊断 !

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Known as	Thymidine kinase; cytosolic;TK1
Derived from	Human Cells
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,1mM DTT,2mM EDTA, 10% Glycerol, pH 7.5.
Storage	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.
Endotoxin	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background	Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during post-translational modification. Two forms of this protein have been identified in animal cells, one in cytosol TK1 and one in mitochondria TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle, while it is very low in resting cells. TK1 acts as a homotetramer, and can transform thymidime to thymidine 5'-phosphate with the help of ATP
规格	10ug50ug500ug1mg

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