Recombinant Human Bcl-2-like Protein 11/BIML-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

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热门关键词：白介素 gibco ELISA试剂盒胎牛血清移液器 ※本公司产品仅供科研实验研究使用，不用于临床诊断 !

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上海极威生物科技有限公司　公司地址:上海市崇明县长兴镇潘园公路1800号2号楼9703室

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Known as	Bcl-2-like protein 11; Bcl2-L-11; Bcl2-interacting mediator of cell death; BCL2L11; BIM; BIML
Derived from	E.coli
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0.
Storage	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.
Endotoxin	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background	BIML is one of several splice variants of BIM, a proapoptotic protein belonging to the BH-3 domain-only subgroup of Bcl-2 family members. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BIML is thought to promote apoptosis by binding and inhibiting the activity of anti-apoptotic Bcl-2 family members, thereby inducing the release of cytochrome c from mitochondria. BIML is normally sequestered in an inactive conformation from anti-apoptotic Bcl-2 family members through binding to the microtubule-associated dynein motor complex. Certain apoptotic stimuli release BIML from microtubules to neutralize anti-apoptotic Bcl-2 family members, allowing for the initiation of apoptosis.
规格	10ug50ug500ug1mg

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