Recombinant Human Insulysin/IDE-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

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热门关键词：白介素 gibco ELISA试剂盒胎牛血清移液器 ※本公司产品仅供科研实验研究使用，不用于临床诊断 !

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上海极威生物科技有限公司　公司地址:上海市崇明县长兴镇潘园公路1800号2号楼9703室

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Known as	Insulin-Degrading Enzyme; Abeta-Degrading Protease; Insulin Protease; Insulinase; Insulysin; IDE
Derived from	Human Cells
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,0.05%Brij35,10%Glycerol,pH7.5.
Storage	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.
Endotoxin	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background	Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.
规格	10ug50ug500ug1mg

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