Recombinant Human MMP-1/Interstitial collagenase-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

0 我的购物车

热门关键词：白介素 gibco ELISA试剂盒胎牛血清移液器 ※本公司产品仅供科研实验研究使用，不用于临床诊断 !

注意：

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。

2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。

我要询价

*联系方式：

(可以是QQ、MSN、电子邮箱、电话等，您的联系方式不会被公开)

*内容：

上海极威生物科技有限公司　公司地址:上海市崇明县长兴镇潘园公路1800号2号楼9703室

邮箱：435399850@qq.com 电话：021-80186165 手机：16602115336

Known as	Interstitial Collagenase; Fibroblast Collagenase; Matrix Metalloproteinase-1; MMP-1; MMP1; CLG
Derived from	Human Cells
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 5.5.Note: The proenzyme needs to be activated by APMA.
Storage	Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles.
Endotoxin	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Background	Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts, keratinocytes, endothelial cells, monocytes and macrophages. MMP1 contains several distinct domains: a prodomain that is cleaved upon activation, a catalytic domain containing the zinc binding site, a short hinge region, and a carboxyl terminal (hemopexin like) domain. MMP-1 can degrade a broad range of substrates including types I, II, III, VII, VIII, and X collagens as well as casein, gelatin, α1 antitrypsin, myelin basic protein, L-Selectin, pro-TNF, IL1, IGFBP3, IGFBP5, pro-MMP2, and pro-MMP9. A significant role of MMP1 is the degradation of fibrillar collagens in extracellular matrix remodeling, characterized by the cleavage of the interstitial collagen triple helix into 3/4, 1/4 fragments. MMP1 may also be involved in enzyme cascades, cytokine regulation and cell surface molecule modulation.
规格	10ug50ug500ug1mg

全部分类