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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant Human PIP4K2A/Phosphatidylinositol 5-p250克￥ 11
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Recombinant Human PIP4K2A/Phosphatidylinositol 5-pGV-P02056-10ug￥ 1800.001
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Recombinant Human PIP4K2A/Phosphatidylinositol 5-pGV-P02056-50ug￥ 4720.001
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Recombinant Human PIP4K2A/Phosphatidylinositol 5-pGV-P02056-500ug￥ 13520.001
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Recombinant Human PIP4K2A/Phosphatidylinositol 5-pGV-P02056-1mg￥ 20400.001
产品简介
| Known as | 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha;Diphosphoinositide kinase 2-alpha;PIP5KIII;Phosphatidylinositol 5-phosphate 4-kinase type II alpha;PtdIns(4)P-5-kinase B isoform;PtdIns(4)P-5-kinase C isoform;PtdIns(5)P-4-kinase isoform 2-alpha |
| Derived from | Human Cells |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
| Background | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PIP4K2A) is a member of the phosphatidylinositol-4-phosphate 5-kinase family. It contains 1 PIPK domain and is expressed ubiquitously, with high levels in the brain. It catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). It may exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. It may regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation, negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. It also involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size. |
| 规格 | 10ug50ug500ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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