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Recombinant Mouse IL-1RA/IL-1RN/Interleukin-1 Rece250克¥ 11
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Recombinant Mouse IL-1RA/IL-1RN/Interleukin-1 ReceGV-P02073-10ug¥ 1800.001
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Recombinant Mouse IL-1RA/IL-1RN/Interleukin-1 ReceGV-P02073-50ug¥ 4720.001
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Recombinant Mouse IL-1RA/IL-1RN/Interleukin-1 ReceGV-P02073-500ug¥ 13520.001
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Recombinant Mouse IL-1RA/IL-1RN/Interleukin-1 ReceGV-P02073-1mg¥ 18800.001
产品简介
Known as | IL-1RN;IL-1ra;IRAP;IL1 inhibitor;Il1rn;Interleukin-1 Receptor Antagonist Protein |
Derived from | E.coli |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
Background | Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26% and 19% identity with its homologues IL-1 beta and IL-1 alpha, respectively. Il1rn can Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling, but has no interleukin-1 like activity. Recently, an recombinant human Il1rn protein is used in the treatment of rheumatoid arthritis, an autoimmune disease in which IL-1 plays a key role. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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