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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant Cynomolgus Siglec-5/CD170/CD33L2/CD33100克/500克/5克¥ 11
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Recombinant Cynomolgus Siglec-5/CD170/CD33L2/CD33GV-P02161-10ug¥ 1800.001
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Recombinant Cynomolgus Siglec-5/CD170/CD33L2/CD33GV-P02161-50ug¥ 4720.001
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Recombinant Cynomolgus Siglec-5/CD170/CD33L2/CD33GV-P02161-500ug¥ 13520.001
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Recombinant Cynomolgus Siglec-5/CD170/CD33L2/CD33GV-P02161-1mg¥ 20400.001
产品简介
Known as | Sialic acid-binding Ig-like lectin 5; Siglec-5 |
Derived from | Human Cells |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH8.0. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution | Dissolve the lyophilized protein in distilled water. |
Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
Background | Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene, Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence, a439aa extracellular domain (ECD) with three Ig-like domains, a transmembrane region and a cytoplasma tail. No Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds equally to alpha-2,3-linked and alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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