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产品名称
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单价(含增值税)
库存(PCS)
起订数量
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Recombinant Human VAP-1/SSAO/HPAO/AOC348T/96T¥ 0.001
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Recombinant Human VAP-1/SSAO/HPAO/AOC3GV-P02329-10ug¥ 2699.001
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Recombinant Human VAP-1/SSAO/HPAO/AOC3GV-P02329-50ug¥ 9607.001
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Recombinant Human VAP-1/SSAO/HPAO/AOC3GV-P02329-500ug¥ 37635.001
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Recombinant Human VAP-1/SSAO/HPAO/AOC3GV-P02329-1mg¥ 57256.001
产品简介
Known as | Membrane primary amine oxidase; Copper amine oxidase; Semicarbazide-sensitive amine oxidase; Vascular adhesion protein 1; AOC3; VAP-1; SSAO; HPAO |
Derived from | Human Cells |
Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, pH8.0. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Reconstitution | Dissolve the lyophilized protein in distilled water. |
Endotoxin | Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test. |
Background | Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflammation. This rise in metabolic products contributes to generating advanced glycation end-products and oxidative stress along with the monoamine detoxification in the organism. It is highly expressed on the endothelium of the lung and trachea, and absent from leukocytes and epithelial cells. Membrane-bound VAP-1 releases an active, soluble form of the protein, which may be conducive to increased inflammation and the progression of many vascular disorders. In particular, elevation of VAP-1 activity and the increased enzymatic-mediated deamination is proposed to play a role in renal and vascular disease, oxidative stress, acute and chronic hyperglycemia, and diabetes complications. |
规格 | 10ug50ug500ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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