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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human RAB3A protein48T/96T￥ 0.001
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Recombinant human RAB3A proteinGV-P03759-10ug￥ 560.001
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Recombinant human RAB3A proteinGV-P03759-50ug￥ 1120.001
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Recombinant human RAB3A proteinGV-P03759-100ug￥ 1800.001
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Recombinant human RAB3A proteinGV-P03759-1mg￥ 11200.001
产品简介
| 基因名 | RAB3A |
| 英文全称 | RAB3A, member RAS oncogene family |
| 别称 | / |
| 中文名称 | RAB3A,RAS致癌基因家族成员 |
| Uniprot | P20336 |
| GeneID | 5864 |
| 交叉反应(推测) | Human Mouse Rat (Pig Bovine) |
| 氨基酸大小 | 25kDa |
| 表达氨基酸 | 1-220aa |
| Background | Small GTP-binding protein that plays a central role in regulated exocytosis and secretion.Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane.Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane.Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed.Stimulates insulin secretion through interaction with RIMS2 or RPH3AL effectors in pancreatic beta cells.Regulates calcium-dependent lysosome exocytosis and plasma membrane repair (PMR) via the interaction with 2 effectors, SYTL4 and myosin-9/MYH9.Acts as a positive regulator of acrosome content secretion in sperm cells by interacting with RIMS1.Plays also a role in the regulation of dopamine release by interacting with synaptotagmin I/SYT. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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