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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human SIX1 protein100克/500克￥ 11
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Recombinant human SIX1 proteinGV-P03781-10ug￥ 560.001
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Recombinant human SIX1 proteinGV-P03781-50ug￥ 1120.001
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Recombinant human SIX1 proteinGV-P03781-100ug￥ 1800.001
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Recombinant human SIX1 proteinGV-P03781-1mg￥ 11200.001
产品简介
| 基因名 | SIX1 |
| 英文全称 | Homeobox protein SIX1 |
| 别称 | BOS3;DFNA23;TIP39 |
| 中文名称 | 同源盒蛋白SIX1 |
| Uniprot | Q15475 |
| GeneID | 6495 |
| 交叉反应(推测) | Human Mouse |
| 氨基酸大小 | 32kDa |
| 表达氨基酸 | 1-284aa |
| Background | Transcription factor that is involved in the regulation of cell proliferation, apoptosis and embryonic development.Plays an important role in the development of several organs, including kidney, muscle and inner ear.Depending on context, functions as transcriptional repressor or activator.Lacks an activation domain, and requires interaction with EYA family members for transcription activation.Mediates nuclear translocation of EYA1 and EYA2.Binds the 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the MYOG promoter.Regulates the expression of numerous genes, including MYC, CCND1 and EZR.Acts as activator of the IGFBP5 promoter, probably coactivated by EYA2.Repression of precursor cell proliferation in myoblasts is switched to activation through recruitment of EYA3 to the SIX1-DACH1 complex.During myogenesis, seems to act together with EYA2 and DACH2.Regulates the expression of CCNA1. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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