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单价(含增值税)
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起订数量
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Recombinant human HAAO protein48T/96T¥ 0.001
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Recombinant human HAAO proteinGV-P03816-10ug¥ 560.001
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Recombinant human HAAO proteinGV-P03816-50ug¥ 1120.001
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Recombinant human HAAO proteinGV-P03816-100ug¥ 1800.001
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Recombinant human HAAO proteinGV-P03816-1mg¥ 11200.001
产品简介
| 基因名 | HAAO |
| 英文全称 | 3-hydroxyanthranilate 3,4-dioxygenase |
| 别称 | HAAO;3-HAO;HAO |
| 中文名称 | 3-羟基邻氨基苯甲酸3,4-二加氧酶 |
| Uniprot | P46952 |
| GeneID | 23498 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Zebrafish Cat Pig Horse) |
| 氨基酸大小 | 33kDa |
| 表达氨基酸 | 1-286aa |
| Background | 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron.It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system.HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid.QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors.Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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