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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human PLEKHO1 protein500克/25公斤/100克￥ 11
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Recombinant human PLEKHO1 proteinGV-P03821-10ug￥ 560.001
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Recombinant human PLEKHO1 proteinGV-P03821-50ug￥ 1120.001
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Recombinant human PLEKHO1 proteinGV-P03821-100ug￥ 1800.001
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Recombinant human PLEKHO1 proteinGV-P03821-1mg￥ 11200.001
产品简介
| 基因名 | PLEKHO1 |
| 英文全称 | pleckstrin homology domain containing, family O member 1 |
| 别称 | CKIP-1;OC120 |
| 中文名称 | pleckstrin同源物结构域家族O成员1 |
| Uniprot | Q53GL0 |
| GeneID | 51177 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Chicken Zebrafish) |
| 氨基酸大小 | 46kDa |
| 表达氨基酸 | 1-409aa |
| Background | Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by the PLEKHO1 gene.PLEKHO1 has been shown to interact with Casein kinase 2, alpha 1 and SMURF1.It plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP).Appears to target ATM to the plasma membrane,and also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.The protein implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF.When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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