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产品简介
| 基因名 | IGHA1 |
| 英文全称 | immunoglobulin heavy constant alpha 1 |
| 别称 | / |
| 中文名称 | 免疫球蛋白重常数α1 |
| Uniprot | P01876 |
| GeneID | 3493 |
| 交叉反应(推测) | Human (Gorilla) |
| 氨基酸大小 | 38kDa |
| 表达氨基酸 | 155-501aa |
| Background | Constant region of immunoglobulin heavy chains.Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens.The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.Ig alpha is the major immunoglobulin class in body secretions. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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