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Recombinant human KRT222P protein500克¥ 11
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Recombinant human KRT222P proteinGV-P03851-10ug¥ 560.001
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Recombinant human KRT222P proteinGV-P03851-50ug¥ 1120.001
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Recombinant human KRT222P proteinGV-P03851-100ug¥ 1800.001
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Recombinant human KRT222P proteinGV-P03851-1mg¥ 11200.001
产品简介
| 基因名 | KRT222P |
| 英文全称 | Keratin-like protein KRT222 |
| 别称 | KA21;KRT222P;MGC45562 |
| 中文名称 | Keratin样蛋白KRT222 |
| Uniprot | Q8N1A0 |
| GeneID | 125113 |
| 交叉反应(推测) | Human |
| 氨基酸大小 | 34kDa |
| 表达氨基酸 | 1-295aa |
| Background | KRT222, also known as KRT222P.KRT222 is a 295 amino acid protein belonging to the intermediate filament family.The gene encoding KRT222P has been listed as a pseudogene, however it has not been established that the protein is not translated, and is therefore treated as a protein coding gene.Existing as two alternatively spliced isoforms, the gene encoding KRT222P maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death.Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome.Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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