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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human MMS19 protein250克/5克￥ 11
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Recombinant human MMS19 proteinGV-P03981-10ug￥ 560.001
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Recombinant human MMS19 proteinGV-P03981-50ug￥ 1120.001
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Recombinant human MMS19 proteinGV-P03981-100ug￥ 1800.001
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Recombinant human MMS19 proteinGV-P03981-1mg￥ 11200.001
产品简介
| 基因名 | MMS19 |
| 英文全称 | MMS19 nucleotide excision repair homolog (S. cerevisiae) |
| 别称 | hMMS19;MET18;MMS19L |
| 中文名称 | MMS19核苷酸切除修复蛋白同源物 |
| Uniprot | Q96T76 |
| GeneID | 64210 |
| 交叉反应(推测) | Human Mouse (Bovine A.thaliana) |
| 氨基酸大小 | 32kDa |
| 表达氨基酸 | 1-294aa |
| Background | Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity.In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER), homologous recombination-mediated double-strand break DNA repair, DNA replication and RNA polymerase II (POL II) transcription (PubMed:22678362, PubMed:22678361, PubMed:29225034, PubMed:23585563).As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD (PubMed:20797633).Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery (PubMed:11279242). |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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