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Recombinant human HLA-DRB3 protein96T/48T¥ 0.001
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Recombinant human HLA-DRB3 proteinGV-P04036-10ug¥ 560.001
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Recombinant human HLA-DRB3 proteinGV-P04036-50ug¥ 1120.001
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Recombinant human HLA-DRB3 proteinGV-P04036-100ug¥ 1800.001
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Recombinant human HLA-DRB3 proteinGV-P04036-1mg¥ 11200.001
产品简介
| 别称 | HLA-DRB3; HLA-DR1B; HLA-DR3B; major histocompatibility complex, class II, DR beta 3 |
| Background | HLA-DRB3 belongs to the HLA class II beta chain paralogues.This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane.It plays a central role in the immune system by presenting peptides derived from extracellular proteins.Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages).The beta chain is approximately 26-28 kDa and its gene contains 6 exons.Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities.Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation.DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5.The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted.There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| 基因名 | GLIPR1 |
| 英文全称 | GLI pathogenesis-related 1 |
| 中文名称 | 胶质细胞发病相关蛋白1 |
| Uniprot | P48060 |
| GeneID | 11010 |
| 交叉反应(推测) | Human Mouse |
| 氨基酸大小 | 29kDa |
| 表达氨基酸 | 1-265aa |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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