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Recombinant human MARK3 protein48T/96T¥ 36001
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Recombinant human MARK3 proteinGV-P04080-10ug¥ 560.001
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Recombinant human MARK3 proteinGV-P04080-50ug¥ 1120.001
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Recombinant human MARK3 proteinGV-P04080-100ug¥ 1800.001
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Recombinant human MARK3 proteinGV-P04080-1mg¥ 11200.001
产品简介
| 基因名 | MARK3 |
| 英文全称 | MAP/microtubule affinity-regulating kinase 3 |
| 别称 | C-TAK1; Cdc25C associated protein kinase 1; Cdc25C-associated protein kinase 1; cTAK1; ELKL motif kinase 2; EMK-2; Emk2; ETK 1; KIAA4230; KP78; MAP microtubule affinity regulating kinase 3; MAP/microtubule affinity-regulating kinase 3; Mark3; MARK3_HUMAN; Par 1a; PAR1A; Protein kinase STK10; Ser/Thr protein kinase PAR-1; Serine threonine protein kinase p78; Serine/threonine-protein kinase p78; SerThr protein kinase PAR 1; |
| 中文名称 | 微管亲和调控蛋白激酶3 |
| Uniprot | P27448 |
| GeneID | 4140 |
| 交叉反应(推测) | Human Mouse Rat |
| 氨基酸大小 | 39kDa |
| 表达氨基酸 | 42-392aa |
| Background | Serine/threonine-protein kinase (PubMed:23666762).Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4.Phosphorylates the microtubule-associated protein MAPT/TAU (PubMed:23666762).Phosphorylates CDC25C on 'Ser-216'.Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus (PubMed:16980613).Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1.Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1 (PubMed:28087714). |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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