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产品名称
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库存(PCS)
起订数量
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Recombinant human TTC29 protein48T/96T￥ 36001
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Recombinant human TTC29 proteinGV-P04115-10ug￥ 560.001
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Recombinant human TTC29 proteinGV-P04115-50ug￥ 1120.001
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Recombinant human TTC29 proteinGV-P04115-100ug￥ 1800.001
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Recombinant human TTC29 proteinGV-P04115-1mg￥ 11200.001
产品简介
| 基因名 | TTC29 |
| 英文全称 | tetratricopeptide repeat domain 29 |
| 别称 | TPR repeat protein 29;Protein TBPP2A;Testis development protein NYD-SP14 |
| 中文名称 | 四三肽重复结构域29 |
| Uniprot | Q8NA56 |
| GeneID | 83894 |
| 交叉反应(推测) | Human Mouse Rat |
| 氨基酸大小 | 35kDa |
| 表达氨基酸 | 1-320aa |
| Background | This locus has a highly complex imprinted expression pattern.It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons.Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression.An antisense transcript is produced from an overlapping locus on the opposite strand.One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region.In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex.Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses.Multiple transcript variants encoding different isoforms have been found for this gene.Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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