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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human UFD1L protein48T/96T￥ 36001
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Recombinant human UFD1L proteinGV-P04132-10ug￥ 560.001
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Recombinant human UFD1L proteinGV-P04132-50ug￥ 1120.001
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Recombinant human UFD1L proteinGV-P04132-100ug￥ 1800.001
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Recombinant human UFD1L proteinGV-P04132-1mg￥ 11200.001
产品简介
| 基因名 | UFD1L |
| 英文全称 | ubiquitin fusion degradation 1 like (yeast) |
| 别称 | UB fusion protein 1；UFD1L |
| 中文名称 | 泛素融合降解样蛋白1 |
| Uniprot | Q92890 |
| GeneID | 7353 |
| 交叉反应(推测) | Human Mouse Rat |
| 氨基酸大小 | 34kDa |
| 表达氨基酸 | 1-308aa |
| Background | Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins.The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome.The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.It may be involved in the development of some ectoderm-derived structures (By similarity).Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to DDX58/RIG-I and recruits RNF125 to promote ubiquitination and degradation of DDX58/RIG-I. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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