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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human WDR37 protein48T/96T￥ 36001
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Recombinant human WDR37 proteinGV-P04166-10ug￥ 560.001
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Recombinant human WDR37 proteinGV-P04166-50ug￥ 1120.001
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Recombinant human WDR37 proteinGV-P04166-100ug￥ 1800.001
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Recombinant human WDR37 proteinGV-P04166-1mg￥ 11200.001
产品简介
| 基因名 | WDR37 |
| 英文全称 | WD repeat domain 37 |
| 别称 | KIAA0982 |
| 中文名称 | 富含WD重复结构域蛋白37 |
| Uniprot | Q9Y2I8 |
| GeneID | 22884 |
| 交叉反应(推测) | Human Mouse (Gorilla) |
| 氨基酸大小 | 29kDa |
| 表达氨基酸 | 1-265aa |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily.This receptor contains a death domain.It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10.The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis.This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells.Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD).The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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