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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human UGCG protein48T/96T￥ 36001
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Recombinant human UGCG proteinGV-P04185-10ug￥ 560.001
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Recombinant human UGCG proteinGV-P04185-50ug￥ 1120.001
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Recombinant human UGCG proteinGV-P04185-100ug￥ 1800.001
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Recombinant human UGCG proteinGV-P04185-1mg￥ 11200.001
产品简介
| 基因名 | UGCG |
| 英文全称 | UDP-glucose ceramide glucosyltransferase |
| 别称 | GLCT-1;GCS; |
| 中文名称 | UDP-葡萄糖神经酰胺葡萄糖基转移酶 |
| Uniprot | Q16739 |
| GeneID | 7357 |
| 交叉反应(推测) | Human Mouse Rat |
| 氨基酸大小 | 28kDa |
| 表达氨基酸 | 1-250aa |
| Background | Catalyzes at the cytosolic surface of the Golgi, the initial step of the glucosylceramide-based glycosphingolipid/GSL synthetic pathway, the transfer of glucose from UDP-glucose to ceramide to produce glucosylceramide/GlcCer.Glucosylceramide is the core component of glycosphingolipids/GSLs, amphipathic molecules consisting of a ceramide lipid moiety embedded in the outer leaflet of the membrane, linked to one of hundreds of different externally oriented oligosaccharide structures.Glycosphingolipids are essential components of membrane microdomains that mediate membrane trafficking and signal transduction.They are implicated in many fundamental cellular processes, including growth, differentiation, migration, morphogenesis, cell-to-cell and cell-to-matrix interactions.They are required for instance in the proper development and functioning of the nervous system.As an example of their role in signal transduction, they regulate the leptin receptor/LEPR in the leptin-mediated signaling pathway.They also play an important role in the establishment of the skin barrier regulating keratinocyte differentiation and the proper assembly of the cornified envelope.The biosynthesis of GSLs is also required for the proper intestinal endocytic uptake of nutritional lipids (By similarity). |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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