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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human USP18 protein48T/96T￥ 36001
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Recombinant human USP18 proteinGV-P04200-10ug￥ 560.001
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Recombinant human USP18 proteinGV-P04200-50ug￥ 1120.001
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Recombinant human USP18 proteinGV-P04200-100ug￥ 1800.001
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Recombinant human USP18 proteinGV-P04200-1mg￥ 11200.001
产品简介
| 基因名 | USP18 |
| 英文全称 | ubiquitin specific peptidase 18 |
| 别称 | 43 kDa ISG15 specific protease; 43 kDa ISG15-specific protease; EC 3.1.2.; hUBP43; Interferon Stimulated Gene 43 kD; ISG15 Specific Processing Protease; ISG15-specific-processing protease; ISG43; Ubiquitin Specific Peptidase 18; Ubiquitin Specific Protease 18 43 kD; Ubiquitin Specific Protease 18; Ubl carboxyl terminal hydrolase 18; Ubl carboxyl-terminal hydrolase 18; Ubl thioesterase 18; Ubl thiolesterase 18; Ubp15; UBP18_HUMAN; USP18; |
| 中文名称 | 泛素特异性肽酶18 |
| Uniprot | Q9UMW8 |
| GeneID | 11274 |
| 交叉反应(推测) | Human Mouse (Gorilla) |
| 氨基酸大小 | 41kDa |
| 表达氨基酸 | 1-372aa |
| Background | The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates.It is highly expressed in liver and thymus, and is localized to the nucleus.This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease.Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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