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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human TMEM30A protein48T/96T￥ 36001
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Recombinant human TMEM30A proteinGV-P04217-10ug￥ 560.001
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Recombinant human TMEM30A proteinGV-P04217-50ug￥ 1120.001
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Recombinant human TMEM30A proteinGV-P04217-100ug￥ 1800.001
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Recombinant human TMEM30A proteinGV-P04217-1mg￥ 11200.001
产品简介
| 基因名 | TMEM30A |
| 英文全称 | transmembrane protein 30A |
| 别称 | C6orf67; CDC50A; Cell cycle control protein 50A; FLJ10856; P4 ATPase flippase complex beta subunit TMEM30A; TMEM30A; |
| 中文名称 | 跨膜蛋白30A |
| Uniprot | Q9NV96 |
| GeneID | 55754 |
| 交叉反应(推测) | Human Mouse Rat (Gorilla Bovine Chicken) |
| 氨基酸大小 | 36kDa |
| 表达氨基酸 | 1-326aa |
| Background | Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids.Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules.The beta subunit may assist in binding of the phospholipid substrate.Required for the proper folding, assembly and ER to Golgi exit of the ATP8A2:TMEM30A flippase complex.ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth, and, reconstituted to liposomes, predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE).The ATP8A1:TMEM30A flippase complex seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane.Required for the formation of the ATP8A2, ATP8B1 and ATP8B2 P-type ATPAse intermediate phosphoenzymes.Involved in uptake of platelet-activating factor (PAF), synthetic drug alkylphospholipid edelfosine, and, probably in association with ATP8B1, of perifosine.Also mediates the export of alpha subunits ATP8A1, ATP8B1, ATP8B2, ATP8B4, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B and ATP11C from the ER to other membrane localizations. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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