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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human GNA13 protein48T/96T￥ 36001
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Recombinant human GNA13 proteinGV-P04220-10ug￥ 560.001
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Recombinant human GNA13 proteinGV-P04220-50ug￥ 1120.001
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Recombinant human GNA13 proteinGV-P04220-100ug￥ 1800.001
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Recombinant human GNA13 proteinGV-P04220-1mg￥ 11200.001
产品简介
| 基因名 | GNA13 |
| 英文全称 | Guanine nucleotide-binding protein subunit alpha-13 |
| 别称 | GNA13;G13 |
| 中文名称 | 鸟嘌呤核苷酸结合蛋白亚单位α-13 |
| Uniprot | Q14344 |
| GeneID | 10672 |
| 交叉反应(推测) | Human Mouse Rat |
| 氨基酸大小 | 39kDa |
| 表达氨基酸 | 1-350aa |
| Background | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:21212405, PubMed:19151758, PubMed:16388592).Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:16388592).GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (PubMed:19151758, PubMed:21212405).Promotes tumor cell invasion and metastasis by activating Rho/ROCK signaling pathway (By similarity).Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (By similarity). |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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