Recombinant human RBM4 protein-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

热门关键词：白介素 gibco ELISA试剂盒胎牛血清移液器 ※本公司产品仅供科研实验研究使用，不用于临床诊断 !

产品简介

基因名	RBM4
英文全称	RNA binding motif protein 4
别称	dkfzp547k0918; hLark; lark; Lark homolog; lark homologue; mgc75138; RBM4; rbm4 lark; RBM4_HUMAN; RNA binding motif 4; RNA binding motif 4a; RNA-binding motif protein 4; RNA-binding motif protein 4a; RNA-binding protein 4;
中文名称	RNA结合基序蛋白4
Uniprot	Q9BWF3
GeneID	5936
交叉反应(推测)	Human Mouse Rat (Bovine Pig Rabbit)
氨基酸大小	40kDa
表达氨基酸	1-365aa
Background	RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation.Modulates alternative 5'-splice site and exon selection.Acts as a muscle cell differentiation-promoting factor.Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation.Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin.Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs.Required for the translational activation of PER1 mRNA in response to circadian clock.Binds directly to the 3'-UTR of the PER1 mRNA.Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation.Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress.Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions.Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs.Associates with miRNAs during muscle cell differentiation.Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro.
Application	Immunology research
Derived from	E.coli
Purification	NI-NTA affinity purification
Formulation	Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0.
Shipping	The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage	Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution	Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity	Purity≥85% as determined by reducing SDS-PAGE.
Endotoxin	/
Bioactive	Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.)
规格	10ug50ug100ug1mg