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Recombinant human IGHM protein48T/96T¥ 36001
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Recombinant human IGHM proteinGV-P04236-10ug¥ 560.001
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Recombinant human IGHM proteinGV-P04236-50ug¥ 1120.001
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Recombinant human IGHM proteinGV-P04236-100ug¥ 1800.001
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Recombinant human IGHM proteinGV-P04236-1mg¥ 11200.001
产品简介
| 基因名 | IGHM |
| 英文全称 | immunoglobulin heavy constant mu |
| 别称 | / |
| 中文名称 | 免疫球蛋白重链μ |
| Uniprot | P01871 |
| GeneID | 3507 |
| 交叉反应(推测) | Human Mouse |
| 氨基酸大小 | 39kDa |
| 表达氨基酸 | 248-597aa |
| Background | The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases.Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition.This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb.Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation.High level expression of this gene was observed in ovarian and testicular tumors.Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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