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产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
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Recombinant human PTENP1 protein48T/96T￥ 36001
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Recombinant human PTENP1 proteinGV-P04258-10ug￥ 560.001
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Recombinant human PTENP1 proteinGV-P04258-50ug￥ 1120.001
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Recombinant human PTENP1 proteinGV-P04258-100ug￥ 1800.001
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Recombinant human PTENP1 proteinGV-P04258-1mg￥ 11200.001
产品简介
| 基因名 | PTENP1 |
| 英文全称 | phosphatase and tensin homolog pseudogene 1 |
| 别称 | 10q23del;BZS;CWS1;DEC;GLM2;MHAM;MMAC1;PTEN1;TEP1;PTEN;PTENbeta |
| 中文名称 | 同源性磷酸酶-张力蛋白假基因 |
| Uniprot | / |
| GeneID | 11191 |
| 交叉反应(推测) | / |
| 氨基酸大小 | 43kDa |
| 表达氨基酸 | 1-370aa |
| Background | This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency.The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase.It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases.Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates.It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane.This longer isoform may help regulate energy metabolism in the mitochondria.A pseudogene of this gene is found on chromosome 9.Alternative splicing and the use of multiple translation start codons results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2015] |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban't be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug50ug100ug1mg |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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