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产品简介
| 中文名称 | 小鼠上皮细胞粘附分子检测试剂盒 |
| 储存条件 | 2-8℃ |
| 有效期 | 6个月 |
| 英文名称 | Mouse EpCAM ELISA KIT |
| 英文别名 | CD326 ; EGP ; EGP-2 ; Egp314 ; Ep-CAM ; EpCAM1 ; GA733-2 ; gp40 ; Ly74 ; Tacsd1 ; Tacstd1; TROP1 ；EpCAM |
| 检测范围 | 156.25-10000pg/ml |
| 灵敏度 | 78.125pg/ml |
| 背景 | Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type a…transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway. |
| 规格 | 48T96T |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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