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| 中文名称 | 小鼠骨形态发生蛋白3检测试剂盒 |
| 储存条件 | 2-8℃ |
| 有效期 | 6个月 |
| 英文名称 | Mouse BMP-3 ELISA KIT |
| 英文别名 | BMP3; BMP-3; BMP3A; BMP-3A; bone morphogenetic protein 3 (osteogenic); bone morphogenetic protein 3; Bone morphogenetic protein 3A; bone morphogenetic protein-3; Osteogenin |
| 反应性 | Mouse |
| 样品类型 | 血清/血浆/细胞培养上清 |
| 检测范围 | 18.75-1200pg/ml |
| 灵敏度 | 9.375pg/ml |
| 反应时间 | 3h15min |
| 应用 | ELISA |
| 背景 | Bone morphogenetic protein 3 (BMP3) is a protein in Mouses that is encoded by the BMP3 gene.[1] The protein encoded by this gene is a member of the transforming growth factor beta superfamily. It, like other bone morphogenetic proteins (BMP's) is known for its ability to induce bone and cartilage development. It is a disulfide-linked homodimer. It negatively regulates bone density.[2] BMP3 is an antagonist to other BMP's in the differentiation of osteogenic progenitors.BMP3 suppresses osteoblast differentiation of bone marrow stromal cells via interaction with activin receptor type 2b.[3] It is highly expressed in fractured tissues.[4] BMP3 is downregulated in cholangiocarcinoma (CC) and may act as a biomarker of the cancer.[5] Furthermore, promotor region methylation of the BMP3 gene may cause gastric carcinoma.[6] |
| 规格 | 48T96T |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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