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产品简介
| 中文名称 | 人穿孔素检测试剂盒 |
| 储存条件 | 2-8℃ |
| 有效期 | 6个月 |
| 英文名称 | Human Perforin ELISA KIT |
| 反应性 | Human |
| 样品类型 | Serum, plasma, Cell culture supernatant |
| 灵敏度 | 15pg/ml |
| 检测范围 | 31.2 - 2,000pg/ml |
| 反应时间 | 3h15min |
| 检测目标 | Perforin |
| 应用 | Sandwich ELISA |
| 背景 | Perforin is a pore forming, cytolytic protein that is a component of cytolytic T-cell and NK cell granules. Perforin activates clathrin- and dynamin-dependent endocytosis, which removes perforin and granzymes from the plasm membrane to early endosomes, preserving outer membrane integrity. Perforin facilitates granzyme uptake and avoids the proinflammatory necrotic death of a membrane-damaged cell. Defects in the Perforin gene results in Familial hemophagocytic lymphohistiocytosis (FHL). Perforin-based effector systems are involved not only in the lysis of abnormal cells but also in the down-regulation of cellular immune activation. |
| 规格 | 48T96T |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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