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产品简介
| 储存条件 | 2-8℃ |
| 有效期 | 6个月 |
| 英文名称 | Porcine IL-7 ELISA KIT |
| 英文别名 | IL7; IL-7; IL-7; Interleukin-7; Interleukin 7; Lymphopoietin-1; PBGF |
| 中文别名 | 猪白介素7检测试剂盒 |
| 反应性 | Porcine |
| 样品类型 | 血清/血浆/细胞培养上清 |
| 检测范围 | 15.625-1000 pg/ml |
| 灵敏度 | 3 pg/ml |
| 反应时间 | 3h15min |
| 应用 | ELISA |
| 背景 | IL-7 is a hematopoietic growth factor secreted by stromal cells in the bone marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by normal lymphocytes. IL-7 stimulates the differentiation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells (as opposed to myeloid progenitor cells where differentiation is stimulated by IL-3). It also stimulates proliferation of all cells in the lymphoid lineage. It is important for proliferation during certain stages of B-cell maturation, T and NK cell survival, development and homeostasis. IL-7 is a cytokine important for B and T cell development. IL-7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCR?) during early T cell development.IL-7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that IL-7 plays an essential role in lymphoid cell survival. IL-7 binds to the IL-7 receptor, a heterodimer consisting of Interleukin-7 receptor alpha and common gamma chain receptor, resulting in a cascade of signals important for T-cell development within the thymus and survival within the periphery. IL-7 promotes hematological malignancies (acute lymphoblastic leukemia, T cell lymphoma) |
| 规格 | 48T96T |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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