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| 中文名称 | 人氨基端前心钠肽检测试剂盒 |
| 储存条件 | 2-8℃ |
| 有效期 | 6个月 |
| 英文名称 | Human NT-ProANP ELISA KIT |
| 英文别名 | ANP;ANF;ATFB6;ATRST2;CDD;CDD-ANF;CDP;PND |
| 反应性 | Human |
| 样品类型 | 血清/血浆/细胞培养上清 |
| 检测范围 | 31.25-2000pg/ml |
| 灵敏度 | 15pg/ml |
| 反应时间 | 3h15min |
| 检测目标 | 人氨基端前心钠肽检测试剂盒 |
| 应用 | ELISA |
| 背景 | N-terminal proatrial natriuretic peptide (NT-proANP) is the biologically inactive fragment (98 amino acid) of the ANP prohormone. The secreted prohormone is cleaved producing the N-terminus fragment (NT-proANP) and the atrial natruiretic peptide (ANP). The natriuretic peptides have a common characteristic biochemical structure that consists of a ring of 17 amino acids and a disulfide bridge between 2 cysteine molecules. NT-proANP has been shown to be a useful diagnostic and prognostic tool in heart failure and myocardial infarction. NT-proANP is more stable and has a longer half-life in circulation than ANP. In patients with mild to moderate cardiac disease, NT-proANP levels were increased in response to atrial wall stress increase. Patients diagnosed with diastolic or systolic dysfunction had 2- to 3-fold higher NT-proANP than the control group. A recent study in rat showed that NT-proANP is an excellent biomarker for cardiac hypertrophy. |
| 规格 | 48T96T |
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