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产品简介
英文名称 | Anti-IL16 Polyclonal Antibody |
别名 | LCF;NIL16;PRIL16;prIL-16 |
宿主 | Rabbit |
稀释比例 | IHC 1:50-200. |
Gene ID | 3603 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q14005 |
蛋白分子量 | 59/66/142kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human IL16 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane.Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells. |
Public Immunogen Range | 1215-1265/1332aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | IHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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