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产品简介
| 英文名称 | Anti-NOX4 Polyclonal Antibody |
| 别名 | KOX;KOX-1;RENOX |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 50507 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9NPH5 |
| 蛋白分子量 | 28/32/58/66kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Cell membrane Nucleus |
| 免疫原 | A synthetic peptide of human NOX4 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity. |
| Public Immunogen Range | 400-450/578aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanCowRatMouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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