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| 英文名称 | Anti-NAA10 Polyclonal Antibody |
| 别名 | hARD1;ARD1;ARD1A;TE2 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 8260 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P41227 |
| 蛋白分子量 | 26/25kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of human NAA10 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity . Acetylates amino termini that are devoid of initiator methionine. The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation. Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration. Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development. Acetylates HSPA1A and HSPA1B at 'Lys-77' which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX . Acetylates HIST1H4A. Acts as a negative regulator of sister chromatid cohesion during mitosis. |
| Public Immunogen Range | 55-105/235aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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