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产品简介
英文名称 | Anti-CD47 Polyclonal Antibody |
别名 | IAP;CD47;MER6 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. IF 1:50-200. |
Gene ID | 961 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q08722 |
蛋白分子量 | 35/34/33/32kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cell membrane Cytoplasm |
免疫原 | A synthetic peptide of human CD47 |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. |
Public Immunogen Range | 60-110/323aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIF |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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