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产品简介
英文名称 | Anti-RAB3IP Polyclonal Antibody |
别名 | Rab3A-interacting protein;Rabin-3;SSX2-interacting protein;RABIN8 |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 117177 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q96QF0 |
蛋白分子量 | 53/51/45/43/35/34/33/29kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Cell membrane |
免疫原 | A synthetic peptide of human RAB3IP |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. |
Public Immunogen Range | 270-320/476aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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