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产品简介
英文名称 | Anti-RGR Polyclonal Antibody |
别名 | Retinal G protein coupled receptor (HGNC Symbol) |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 5995 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P47804 |
蛋白分子量 | 28/32kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cell membrane |
免疫原 | Recombinant protein of human RGR |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms |
Public Immunogen Range | 1-291aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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