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产品简介
英文名称 | Anti-ELOC Polyclonal Antibody |
别名 | ELOC;SIII;TCEB1;eloC;elongin-C |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 6921 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | Q15369 |
蛋白分子量 | 12/11kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus |
免疫原 | Recombinant protein of human ELOC |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. |
Public Immunogen Range | 1-113aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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