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产品简介
| 靶标 | ZNF131 |
| 别名 | ZBTB35; pHZ-10 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000. IHC 1:25-100 |
| Gene ID | 7690 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P52739 |
| 蛋白分子量 | 71 kDa |
| 储存液 | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 亚细胞定位 | Nucleus |
| 免疫原 | Fusion protein of human ZNF131 |
| 亚型 | IgG |
| 纯化方法 | Antigen affinity purification |
| 背景资料 | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF131 (Zinc finger protein 131) is a 623 amino acid nuclear protein that contains one BTB (POZ) domain and six C2H2-type zinc fingers. With predominant expression found in brain, it is likely that ZNF131 plays a role as a transcription regulator during development and organogenesis of the adult central nervous system. ZNF131 also represses ER? (Estrogen receptor alpha)-mediated transactivation by interrupting ER? binding to the estrogen-response element. There are two isoforms of ZNF131 that are produced as a result of alternative splicing events. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBELISAIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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