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产品简介
| 靶标 | CNTNAP2 |
| 别名 | CDFE; NRXN4; AUTS15; CASPR2; PTHSL1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000. IHC 1:20-100 |
| Gene ID | 26047 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9UHC6 |
| 蛋白分子量 | 148 kDa |
| 储存液 | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 亚细胞定位 | Cell membrane |
| 免疫原 | Fusion protein of human CNTNAP2 |
| 亚型 | IgG |
| 纯化方法 | Antigen affinity purification |
| 背景资料 | This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBELISAIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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