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| 靶标 | STX5 |
| 别名 | SED5; STX5A |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200 |
| Gene ID | 6811 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13190 |
| 蛋白分子量 | 40 kDa |
| 储存液 | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Fusion protein of human STX5 |
| 亚型 | IgG |
| 纯化方法 | Antigen affinity purification |
| 背景资料 | The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa (long) protein localized to the Golgi complex and endoplasmic reticulum, and a “short” 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBELISAIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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