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产品简介
| 英文名称 | Anti-SHP-2 Monoclonal Antibody |
| 别名 | BPTP3;CFC;JMML;METCDS;NS1;PTP-1D;PTP2C;SH-PTP2;SH-PTP3;SHP2;PTPN11 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50. IP 1:50. |
| Gene ID | 5781 |
| 保存 | Store at –20°C. Do not aliquot the antibody. |
| Swiss Prot | Q06124 |
| 蛋白分子量 | 53/68kDa |
| 储存液 | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 μg/ml BSA, 50% glycerol and less than 0.02% sodium azide. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthesized peptide derived from human SHP-2 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. |
| Public Immunogen Range | A synthesized peptide derived from human SHP-2 |
| 克隆类型 | Monoclonal antibody |
| 交叉反应 | HumanMonkeyRatMouse |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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