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产品简介
| 英文名称 | Anti-MCM7 Polyclonal Antibody |
| 靶标 | MCM7 |
| 别名 | CDC47;MCM2;P1.1-MCM3;P1CDC47;P85MCM;PNAS146;PPP1R104 |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 4176 |
| 保存 | Store at -78°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P33993 |
| 蛋白分子量 | 45/61/81kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.61. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human MCM7 |
| 亚型 | IgG |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 背景资料 | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage. |
| Public Immunogen Range | 485-535/719aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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