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产品简介
英文名称 | Anti-MFNG Polyclonal Antibody |
靶标 | MFNG |
别名 | 3-N-acetylglucosaminyltransferase manic fringe; Beta-1; Beta-1,3-N-acetylglucosaminyltransferase manic fringe; MFNG; MFNG_HUMAN; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. |
Gene ID | 4242 |
保存 | Store at -48°C. Avoid freeze / thaw cycles. |
Swiss Prot | O00587 |
蛋白分子量 | 35/36kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.31. |
亚细胞定位 | Cytoplasm |
免疫原 | A synthetic peptide of human MFNG |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity). |
Public Immunogen Range | 271-321/321 |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanPredicted:Chicken Xenopus laevis ChimpanzeeMouse |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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