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产品简介
| 英文名称 | Anti-SOX12 Polyclonal Antibody |
| 靶标 | SOX12 |
| 别名 | Transcription factor SOX-12;Protein SOX-22;SOX22; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 6666 |
| 保存 | Store at -30°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O15370 |
| 蛋白分子量 | 34kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.13. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human SOX12 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3' (By similarity). Acts as a transcriptional activator (By similarity). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Involved in the differentiation of naive CD4-positive T-cells into peripherally induced regulatory T (pT reg) cells under inflammatory conditions (By similarity). Binds to the promoter region of the FOXP3 gene and promotes its transcription, and might thereby contribute to pT reg cell differentiation in the spleen and lymph nodes during inflammation (By similarity). Plays a redundant role with SOX4 and SOX11 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity). |
| Public Immunogen Range | 265-315/315 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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