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产品简介
英文名称 | Anti-MCM3 Polyclonal Antibody |
靶标 | MCM3 |
别名 | HCC5;P1-MCM3;P1.h;RLFB |
宿主 | Rabbit |
稀释比例 | WB 1:1000-3000. IHC 1:100-300. |
Gene ID | 4172 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P25205 |
蛋白分子量 | 91/96kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Nucleus |
免疫原 | Recombinant protein of human MCM3 |
亚型 | IgG |
纯化方法 | Octanoic acid-ammonium sulfate precipitation |
背景资料 | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation. |
Public Immunogen Range | 459-809aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanMouse |
应用 | WBIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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